IV bottles and irrigation bottles can be made in the Blow-Fill-Seal machine from the same mold by interchanging the seal mold to provide different top geometries. Separate injection molded caps can be welded to the blow/fill/seal container to create a multi-entry format, usually used to introduce a secondary medication into the solution prior to dispensing to the patient.
Special diameter ports can be provided on the bottles to accommodate plastic needle-less spikes, designed for infusion administration. Bottles can be designed with
Large Volume Parenterals are typically injectable products designed for intravenous delivery applications. The large volume parenteral bottles are most often produced from a resin that can be autoclaved, either at 106° C or 121° C.
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